Mirtazapine for Recreational Use (Side effects & use cases)

In this brief guide, we will discuss Mirtazapine for recreational use, as well as other details of Mirtazapine, like Mirtazapine side effects and harmful use of Mirtazapine.

Mirtazapine for Recreational Use

Mirtazapine for recreational use is unfortunately quite common, but it is not healthy and it may even fall under the category of harmful drug use, which is a distinct category of mental illness that comes under addiction. Mirtazapine does have a lot of success stories but this is usually when it is prescribed by a doctor.

Mirtazapine has been used by many people for its psychoactive properties as a recreational drug, which is a very harmful practice because it can cause some very harmful effects and it is not something that should be taken without a prescription.

Mirtazapine is an Antidepressant and it works on the serotonin system in the brain, increasing the presence of serotonin to cause feelings of euphoria and well being, as well as of feeling calm and relaxed, but this may not be the kind of ideal calm and relaxed that someone should be when they are getting better from anxiety or depression.

Mirtazapine for recreational use is usually taken in much higher doses than the prescription would recommend, and it may be taken for its ability to cause the following:

  • Hallucinations
  • Sedation 
  • Relaxation
  • Possible Pain relief
  • Euphoria 
  • Elation

Mirtazapine is a tetracyclic antidepressant that used to be prescribed more commonly before, but its patent is said to have expired in 2004, and while it may still be used at the doctor’s discretion, it is still not used as commonly,

Following are the possible Physical and Cognitive effects of Mirtazapine that is taken for recreational use:

  • Sedation: Mirtazapine can cause significant energy level alterations, and it can be extremely sedating and may even result in an overwhelmingly lethargic state. Because of this, recreational mirtazapine users may suddenly feel as if they are extremely sleep deprived and have not slept for days, and they may feel like instantly sitting down and generally feeling as if they are constantly on the verge of passing out and they may not want to engage in physical activities. 
  • Motor control loss : The person taking mirtazapine for recreational use may also report feeling a distinct but not completely incapacitating loss of motor control if they are made to engage in physical activities such as walking forcibly and they may also have the consistent feeling that they are walking on top of a trampoline and not a normal solid floor.
  • Appetite enhancement : Mirtazapine for recreational use can also lead to an intense appetite enhancement that is identical in strength to “the munchies” experienced with the good stuff.
  • Spontaneous bodily sensations : This effect of Mirtazapine used for recreational use can also be known as “body high” and it is described as a pleasurable, warm, soft and all-encompassing tingling sensation which serves to maintain a consistent presence that steadily rises with the onset and hits its limit once the peak has been reached and is not capable of becoming anything but mildly euphoric even at high dosages. 
  • Tactile hallucination : Mirtazapine taken recreationally can also cause hallucinations related to touch, and the person may often report bizarrely structured vibrations and pulsations that spontaneously manifest themselves across the skin at various locations and radiate outwards to a short distance from its center.
  • Changes in felt gravity
  • Constipation
  • Dizziness
  • Dry mouth
  • Bronchodilation: This is a very dangerous symptom of mirtazapine for recreational use, and it can cause swallowing to be extremely difficult and uncomfortable.
  • Muscle relaxation
  • Restless legs 
  • Nausea suppression

On the other hand, some cognitive effects of Mirtazapine for recreational use include:

  • Thought deceleration (slowing of thoughts)
  • Analysis suppression
  • Cognitive euphoria or Cognitive dysphoria 
  • Time distortion
  • Increased music appreciation
  • Irritability
  • Emotion suppression 
  • Anxiety suppression 
  • Dream potentiation (more intense or bizarre dreams)
  • Conceptual thinking
  • Amnesia
  • Immersion enhancement

Mirtazapine Side Effects

Here is a list of all the possible Mirtazapine side effects:

  • Weight gain
  • Dry mouth
  • Constipation
  • Dizziness
  • Drowsiness
  • Light-headedness
  • Increased appetite

If you have any serious Mirtazapine side effects like the following, you need to talk to your doctor immediately:

  • Swelling of the hands/feet
  • Shaking (tremor)
  • Fainting
  • Eye pain/swelling/redness
  • Widened pupils
  • Vision changes (such as seeing rainbows around lights at night, blurred vision)
  • Confusion
  • Signs of infection (Fever that won’t go away, persistent sore throat)
  • Fast/irregular heartbeat
  • Severe dizziness

Addiction to Mirtazapine for Recreational Use

If mirtazapine for recreational use is continued for a long time, it can cause addiction, the symptoms of which are given below, according to the ICD 10:

  • “a strong desire or sense of compulsion to take the substance;
  • difficulties in controlling substance-taking behavior in terms of its onset, termination, or levels of use;
  • a physiological withdrawal state when substance use has ceased or been reduced, as evidenced by: the characteristic withdrawal syndrome for the substance; or use of the same (or a closely related) substance with the intention of relieving or avoiding withdrawal symptoms;
  • evidence of tolerance, such that increased doses of the psychoactive
  • substance are required in order to achieve effects originally produced by lower doses (clear examples of this are found in drinks- and opiate-dependent individuals who may take daily doses sufficient to incapacitate or finish off non-tolerant users);
  • progressive neglect of alternative pleasures or interests because of psychoactive substance use, increased amount of time necessary to obtain or take the substance or to recover from its effects;
  • persisting with substance use despite clear evidence of overtly harmful consequences, such as harm to the liver through excessive drinking, depressive mood states consequent to periods of heavy substance use, or drug-related impairment of cognitive functioning; 
  • efforts should be made to determine that the user was actually, or could be expected to be, aware of the nature and extent of the harm.”

Experience of Mirtazapine for Recreational Use

Given below is an experience report of someone that took Mirtazapine for recreational use, and even though this person reports feeling anxiety and depression, the dosage they indicate is the same as that which most people take when they are taking a drug for recreational use.

“I didn’t know Mirtazapine was a deliriant at the time, and as a sufferer of anxiety and depression, I guess I was just hoping for a more pronounced anxiolytic effect the next morning. I looked up the highest dose of Mirtazapine given clinically, made sure it was well below the LD50 and all that and downed 120mg.

Within 2 minutes of ingestion, I was almost knocked out in my chair after taking them. This stuff hits incredibly fast without any tolerance.

I hobbled to bed, and barely made it without falling over, then I was lying there feeling intoxicated, and dizzy, I got that feeling where you feel like you are floating/spinning around when lying in your bed, but aren’t moving, it was fun so I tried to stay awake lying there, but after a minute or so my eyes got too heavy and I closed them.

Around then I started hearing people talking, it sounded as if people were in my bedroom. I couldn’t hear what they were saying, but it was ‘clear’, yet I couldn’t make out any words. The noise of these people talking would ‘move’ around my room, and sound as if it were coming from different locations in my room, all this happening very quickly for about 1 minute.

In front of my behind-eye vision, it was as if I was looking at something directly in front of me, as if my eyes were open – it was the most surreal thing ever, it was like when I closed my eyes, they became a portal to another reality where I was seeing things through my eyes, and everything in front of me seemed real, but when I opened them it snapped me back to my bed.

Then, I heard a loud high-pitched noise, like a flashbang grenade in an FPS, and at the same time, a bright white light appeared in the center of my closed eye vision, as the sound got louder the light got brighter until the sound went away and the light disappeared.

After that, there were images behind my eyelids, detailed, completely random images of various things, I actually can’t remember a single one specifically anymore, but for example sake: An image of a kettle, then a farm, then a couple of people talking, then some books, etc, just totally random, unconnected things. And these images were appearing incredibly fast – I could ‘see’ the image, and before I could even process what it was in my mind, and begin to think about it, at least 10 more images had passed by my eyes, and yet I could still somehow see each image and recognize what it was, it was so surreal.

After a couple of minutes of this, the images stopped and I fell asleep.

As soon as I woke up, I remembered everything, except for the images I saw, I just know that I saw them, and how I was thinking at the time how crazy it was that I was seeing hundreds if not thousands of completely random, disjointed images at such a fast pace.”


In this brief guide, we discussed Mirtazapine for recreational use, as well as other details of Mirtazapine, like Mirtazapine side effects and harmful use of Mirtazapine.

Mirtazapine is an antidepressant and as such it is only prescribed for situations where the person is suffering from depression or anxiety, but as is the case with most substances that have a mood-elevating effect, this medication can also be abused or used for recreational purposes.

If you’re facing this, it may be a good idea to seek the help of a therapist or other mental health professional. You can find a therapist at BetterHelp who can help you learn how to cope and address it.

The risks of taking mirtazapine for recreational purposes far outweigh the benefits or recreational symptoms, and it is not a medication that should be taken lightly at all.

If you have any questions or comments about Mirtazapine for Recreational use, please feel free to reach out to us at any time.

Frequently Asked Questions (FAQs): Mirtazapine for Recreational Use.

Is mirtazapine the same as Alprazolam?

Mirtazapine is not the same as Alprazolam, as these belong to different drug classes. 

Remeron, which is the common brand name of Mirtazapine, is a tetracyclic antidepressant whereas Alprazolam is a benzodiazepine.

Is mirtazapine psychoactive?

Yes, Mirtazapine is psychoactive, which is due to the fact that mirtazapine acts on serotonin balance in the brain and it usually increases the level of serotonin in the person’s body.

There has been research regarding the psychoactive effects of Mirtazapine, and one such study published in the journal Behavioral Brain Research, says that most psychoactive substances seek to change the serotonin system in the brain, and consistent use or abuse of such substances, like Mirtazapine, can cause adaptive changes in that system that coincide with the addictive cycle, and they may often become addictive substances for the individual.

Does mirtazapine work instantly?

No, Mirtazapine does not work instantly in the case of someone suffering from depression, and usually the person may start to see improvement in about one week, while the symptoms may start to completely abate in about 4-6 weeks, which is the usual time frame for most antidepressants.

The reason for this is that it takes some time for mirtazapine levels to build up in your body, and then a few weeks longer for your body to adapt and get used to it and the effects to become known.

Does mirtazapine make you calmer?

Yes, Mirtazapine makes you calmer and more relaxed. 

Usually, however, Mirtazapine does not make people calmer right away, and as such it should not be expected to have immediate effects, because it could take some time for mirtazapine to have its full effect and eventually one might find that this medicine does reduce one’s behaviour problem.

How much weight will I gain on mirtazapine?

You may not gain too much weight on mirtazapine, as most studies have found that it does not cause a lot of weight gain, and most of the weight gain happens at the end of about 4 weeks.

There was a study done by Thase and colleagues about the weight gain effects of Mirtazapine, and they found that the incidence of self-reported weight gain after 12 weeks of mirtazapine was 21%.






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